Wednesday, September 12, 2007

Glutathionylation of CII flavoprotein reduces ROS production, lost in ischemia/reperfusion injury

Yeong-Renn Chen, Chwen-Lih Chen, Douglas R Pfeiffer, and Jay L. Zweier
Mitochondrial complex II in post-ischemic heart: Oxidative injury and the role of protein S-glutathionylation
J. Biol. Chem, 10.1074/jbc.M702294200
(Complex II was glutathionylated at C90 which is C46 in the mature sequence, 10 residues from the FAD covalent attachment site and spatially near the surface and near the adenine end of FAD. )